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The Multi Instrument Comparison (MIC) project
Formal title: A cross-national comparison of 8 generic quality of life (QoL) instruments:
NHMRC ID: 1006334
Chief Investigators: Richardson J (Monash University, Australia) Cummins, R (Deakin University, Australia) Olsen, J (University of Tromso, Norway) Kaplan, R (UCLA, USA) Coast, J (University of Birmingham, UK) Schlander, M (Institute for Innovation and Valuation in Health Care, Germany)
Objective: To compare instruments purporting to measure quality of life; to use survey results to discriminate between the 6 multi attribute utility (MAU) instruments which are most commonly used for the economic evaluation of health programs and the allocation of health budgets
Scope:
The instruments, respondents and countries included in the study are summarised in Tables 1-3.
Table 1 Countries and disease areas included in the study
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Countries
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Disease area
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Australia
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Arthritis
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Canada
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Asthma
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Norway
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Cancer
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UK
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Depression
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USA
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Diabetes
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Germany
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Hearing Loss
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Heart problems
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Table 2 General questionnaires
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Items
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Subjective Wellbeing (SWB)
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Personal Wellbeing Index (PWI)
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9
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Integrated Household Survey (IHS)
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5
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Satisfaction with Life Survey (SWLS)
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4
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subtotal
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18
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Multi Attribute Utility (MAU) Instruments
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EQ-5D-5L
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5
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AQoL-8D and AQoL-4D
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44
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HUI3
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8
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15D
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15
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QWB-SA
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77
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MA Non-Utility Instrument
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SF-36
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36
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subtotal
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185
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Capabilities
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ICECAP-A
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5
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Demographics
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23
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Total items in composite instrument
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231
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Table 2a Disease Specific Questionnaires
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Health Condition
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Disease Specific Instruments
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Number of items
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Depression
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DASS21 and K10
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31
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Hearing Loss
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Abbreviated Profile of Hearing Aid Benefit (APHAB)
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24
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Asthma
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Asthma Quality of Life Questionnaire (AQLQ-Sydney)
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20
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Diabetes
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Diabetes-39
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39
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Arthritis
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Arthritis Impact Measurement Scales 2 (AIMS2-SF)
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26
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Heart
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Macnew Heart QoL
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27
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Cancer
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Cancer QLQ C-30
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30
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Table 3 Respondents and sample size
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Australia
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USA
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UK
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Canada
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Norway
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Germany
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Disease free
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265
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321
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298
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328
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288
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260
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Disease Sample
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Depression
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146
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168
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158
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145
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140
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160
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Hearing Loss
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155
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156
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126
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144
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115
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136
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Asthma
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141
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150
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150
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138
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130
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147
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Diabetes
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168
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168
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161
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144
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143
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140
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Arthritis
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163
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179
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159
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139
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130
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159
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Heart
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149
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170
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167
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154
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151
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152
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Cancer
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154
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148
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137
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138
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80
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115
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Project Rationale
(i) Budgets are increasingly guided by economic evaluations which increasingly employ CUA. This technique relies upon multi attribute utility (MAU) instruments to include the quality of life. These instruments produce very different results and the allocation of a budget may depend upon the choice of MAU instrument. (ii) MAU and SWB (happiness) instruments have followed different theoretical and measurement traditions. The fields need integration. As a preliminary step towards determining the most appropriate instrument for measuring the value of health states, the relationship between SWB and MAU instruments should be understood. This project seeks to achieve this.
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